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Frequencies of seropositivity (RF and/or ACPA), erosive disease and concomitant treatment with MTX, or low-dose corticosteroids were similar between groups considering either each biologic separately or biologic class.
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There was no significant difference between groups considering other concomitant diseases (ischemic cardiopathy, diabetes mellitus, systemic arterial hypertension).
The complication rate difference between groups, considered a categorical variable, was analyzed by the two-tailed Fisher's exact test.
Differences between the groups considering new bone formation, soft tissues, and remaining BC were statistically evaluated.
There were no significant differences between the groups considering age and gender.
Independent T test was performed to determine differences between the groups considering MPDD condition.
There were significant overall differences between groups when considering plasma IL-8 and TNF-α.
The enhancement variation statistically differed between groups when considering the absolute variation (P = 0.0014; 95% CI [−53.47; −12.85]).
Differences between groups were considered significant when P < 0.05.
Differences between groups were considered statistically significant at p < 0.05.
Differences between groups were considered to be statistically significant at p < 0.05.
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CEO of Professional Science Editing for Scientists @ prosciediting.com