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Interactions between genotypes were studied by comparing multinomial frequency distributions in mutually exclusive groups.
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Combined effects between two genotypes were studied by creating different variables, each representing the combination of two genotypes, with the putative "low-risk" homozygous combination as reference category.
Relationship between genotypes and the phenotypes were studied by comparing disease manifestation in patients with different combination of mutations.
In the male fertility study, differences between genotypes were determined using the Kruskal-Wallis analysis with Dunn's post hoc test.
Associations between TPH1 genotype and temperament dimensions were studied in patients with major depressive disorder and linear changes were found at both baseline and endpoint.
For primary SE, eight time points during the first six weeks of SE were studied between a responsive genotype (SCA6) and a recalcitrant genotype (ICS1).
A total of 153 females with MA were studied to investigate the association between A118G genotypes and head pain severity.
In addition, the interaction between environment and hybrid genotype has been studied in a number of plants (Arnold, 1997).
However, to our knowledge and the available literature, the interactions between genotypes and environmental factors and between different genotypes have not been studied so far in association with asbestosis.
In this study, the interaction between genotypes was so dramatic that a given male genotype could be among the quickest to mate with one female genotype, yet among the slowest when presented with another female genotype.
Notwithstanding, the difference between genotypes was less dramatic in the in vitro assays than in the mating studies.
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