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Gene promoter DNA methylation and gene expression profiling of arsenite-transformed prostate epithelial cells showed a negative correlation between gene expression changes and DNA methylation changes; however, less than 10% of the genes with increased promoter methylation were downregulated.
Gene promoter DNA methylation and gene expression profiling of arsenite-transformed prostate epithelial cells present a negative correlation between gene expression changes and DNA methylation changes; however, less than 10% of the genes with increased promoter methylation were downregulated.
Correlations between gene expression changes for all possible pairs of tolerant strains.
Our study distinguishes between gene expression changes in RBS cells that are TOR dependent and those that are independent.
These methods are based on a model assuming a linear relationship between gene expression changes and TF-gene binding affinities.
A Spearman rank correlation test was used to assess the correlation between gene expression changes and treatment duration.
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In this study, we demonstrate a correlation between gene expression change and nCpG content divergence between distant species.
A logistic regression model [ 45] was used to evaluate the relationship between gene expression change after aneuploidy and the presence of a protein-protein interaction.
Our analysis shows a clear relationship between gene expression change and nCpG content divergence in two distantly related species, such as human versus mouse.
Indeed, at all scales (gene of interest to 5 Mbp), there was a general tendency though mostly not statistically significant to positive correlation between gene expression change and proximity to chromocenters.
The RAS is calculated by walking down the list and a running-sum statistic is used to capture the correlation between gene expression change (the t-score) and TF binding potential (from ChIP-seq).
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