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To our knowledge, this is the first evaluation of the association between functional SNPs in IL-17A and CWP susceptibility in a Chinese population.
Thus, the exciting results in the GWAS of ESCC and GCA, and the strong biological evidence encouraged us to investigate the association between functional SNPs in PLCE1 and susceptibility to SCCHN.
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Therefore, we investigated the association between potentially functional SNPs in PLCE1 and susceptibility to SCCHN.
However, few reported studies have investigated the association between potentially functional SNPs in both TNF-α and TNFRSF1B and prognosis of NSCLC patients treated with chemoradiotherapy.
We investigated associations between the functional SNPs in DNA repair genes and response and survival in muscle-invasive bladder cancer patients treated with CRT to determine the predictive value of the SNPs in patient selection for bladder conservation therapy.
In this study we examined associations between functional SNPs of the UDP-glucuronosyltransferase 2B (Ugenes genes and prostate cancer risk.
In this present work, we examined associations between functional SNPs of UGT2B17, UGT2B15 and three other related UGT2B SNPs, and prostate cancer risk among African American and Caucasian men.
No linkage disequilibrium exists between FCGR3A CNVs and FCGR3B CNVs (15, 47) or between FCGR3 CNVs and functional SNPs in FcγRIII genes (34).
We could not check LD between rs7489119 and the other functional SNPs in SLCO1B1 because genotype data for these SNPs are not publicly available or monomorphic in Europeans [ 35].
To test the hypothesis that adverse alleles in miRNA-related genes may influence the risk for esophageal cancer, the associations between esophageal cancer risk and 41 potentially functional SNPs in 26 miRNA-related genes were assessed, in a case-control study [ 25].
To assess the relationship between fibroblast IPC and MMP polymorphism status, donor DNA (n = 32) was analyzed for functional SNPs in MMP-1, MMP-3, and MMP-9 genes.
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