Sentence examples for between expression and methylation from inspiring English sources

Figures 9C and D show the nonlinear relationship between expression and methylation in each of the two clusters identified in Figure 9B.

Recent reports also identified positive associations between expression and methylation levels [ 5- 7].

Thus, it is expected to observe an inverse correlation between expression and methylation.

In summary, we observed multiple strong correlations between expression and methylation module eigengenes.

Next, we tested for associations between expression and methylation of FLT1 and KDR in renal cancer tissues.

The significant results in both directions could indicate a bi-directional causal interaction between expression and methylation.

We also identified families of genes showing consistently significant correlations between expression and differential methylation, including 14 genes from the protocadherin family and 16 zinc-finger genes.

Work in other organisms has demonstrated that the presence of CpG islands in the promoter disrupts the relationship between expression and promoter methylation (Varley et al. 2013).

MTO1 was upregulated in ER- cancer types, meanwhile MRPL41 was upregulated in ER+ cancer types, showing an inverse correlation between expression and promoter methylation.

Our data reaffirmed the relationship between gene expression and methylation levels in that heavily methylated genes had a significant tendency towards lower expression levels [ 35].

None of the genes showed a significant correlation (P < 0.05; Spearman correlation) between gene expression and methylation, or between expression and genotype (Fig. 7; Supplementary Material, Figs S2 and S3).