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If a good match is to be sought between experiments and computational predictions in the elastic plastic zone, strain hardening must be included.
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Owing to the variability between experiments and methodologies, statisticians and computational biologists should guide proteomic analyses.
Therefore, by using the evolutionary conservation of positions mutated in the laboratory, it will now be possible for scientists to better understand the reasons for the discordance between the outcomes of laboratory experiments and computational predictions.
Z.L. did the majority of experiments and computational analyses.
J.S., P.W. and G.T. did a part of the experiments and computational analyses.
RD performed most experiments and computational analysis.
SM performed experiments and computational data analysis.
CA performed all sequencing experiments and computational analysis.
GL, JW, AMM, EJL and CAN designed and supervised the experiments and computational analysis.
GY, YH and YW were involved in carrying out experiments and computational analysis.
I conclude that the dynamical hypothesis outlined above permits a particularly close and direct back-and-forth between perceptual experiment and computational theory and thus has the potential to dramatically accelerate our progress in understanding visual function.
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