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For both antibodies low levels of enrichment were observed at the Sox2 TSS, and there was no significant change in relative enrichment between experimental groups at this locus.
To analyse differences between experimental groups at single-gene expression level, the STATA statistical package was used [45].
The treatment was administered for a total of 14 15 days from the day following appearance of the first clinical symptoms of arthritis (clinical scoring ≥1), with no differences in scoring between experimental groups at the onset of treatment.
Body-weight did not differ between experimental groups at baseline (Table 1).
The distribution of mean ICRS scores between experimental groups at 3 different sampling times is shown in Figure 3.
LVSP was not different between experimental groups at any balloon volume, but LVDevP was used as indicator of systolic dysfunction rather than LVSP, because evaluating systolic pressure without considering diastolic preload does not reflect the in vivo situation.
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The total number of granular neurons in the DG did not change between experimental groups Indicating that, at least in the studied temporal frame, diabetes or the differential housing conditions are not able to affect this factor.
From a list of differently correlated metabolites between two experimental groups at a time it was possible to collect pathways between them and together create new sub-networks to describe the network based origin of the differences.
Differences between experimental groups were considered significant at a probability < 0.05 on a two-tailed test; * and ** denote P < 0.05 and P < 0.01 vs. control, respectively.
Differences between experimental groups were considered significant at a p value of less than 0.05 as determined by the analysis of variance (Bonferroni/Dunn) test and the Mann-Whitney test.
There were no differences between the experimental groups at this early stage.
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