Moreover, the model also accounts for the nonlinear dependence between evolutionary rate and dynamical flexibility.
There is a stronger anti-correlation (see Figure 4B) between evolutionary rate and expression level.
The only correlation supported by a careful analysis of the data is between evolutionary rate and protein abundance.
In addition, there was no indication of any interaction between evolutionary rate and the proportion of domestic birds (P > 0.5).
It is possible, of course, that the lack of correlation between evolutionary rate and recombination is a false negative.
Previous works assessing the relationship between evolutionary rate and RSA subdivided sites into groups with comparable RSA and then calculated evolutionary rates separately for each group [ 9, 20].
The two main approaches used are regression analysis between evolutionary rate and phenotypic variation and codon branch-site models with phenotypes assigned to branches.
However, this remaining correlation appears to be due to an incomplete correction for protein abundance rather than a real correlation between evolutionary rate and the number of interactions.
In order to evaluate this claim, we investigated the effect of data set size on the correlation between evolutionary rate and the number of interactions.
In order to explore the relationship between evolutionary rate and phylogenetic signal, we performed Pearson's correlation analysis between α and λ across nine traits.
In animals, several empirical studies suggested that rodents have a higher evolutionary tempo than primates, indicating an inverse relationship between evolutionary rate and generation time [ 5, 6, 10].
