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This study demonstrates the relationship between enhanced expression of the urokinase receptor in colorectal tumor-associated stromal cells and a significant worse patient survival.
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The temporal correlation observed in Schwann cells between migration and the enhanced expression of NGF and LNGFR suggests that NGF and LNGFR may promote Schwann cell migration.
In the present study, a positive correlation between Tregs and the enhanced expression of IL-6 on CD4+ T cells was observed in T2DM patients (P < 0.05) as well as in healthy subjects (P < 0.01) (Table 4).
A role for JNK activation in regulating apoptosis has been proposed (reviewed in [ 45]), and the correlation between JNK activation and enhanced expression of XAF1 is consistent with JNK playing a role in the induction of cell-death pathways in RSV-infected PMФ cells.
To further demonstrate the relationship between lignin accumulation and enhanced expression of genes related to SAM metabolism, we quantified by qRT-PCR the relative levels of transcripts in cells from Pinus pinaster calli that were stimulated to differentiate tracheids in vitro.
We next determined whether there is any correlation between enhanced phosphorylation of Akt, enhanced expression of integrin β3 and metastatic potential of prostate cancer cells.
Studies using samples from a cohort CHIKV-infected patients showed a tight association between high viral load and an enhanced expression of IFN- α/ β and several genes of the type I IFN signaling pathway, such as IRF3, IRF7, and RSAD2 (viperin encoding gene), in patients PBMCs [ 104].
All of the above findings suggest the next logical step in this study: identification of a correlation between positive tissue staining (high incidence of enhanced expression of GIPC1 in malignant tumors) and cancer specific autoantibody levels in ovarian and breast patients' sera targeting the GIPC1 antigen.
Imbalanced activity between MMPs and tissue inhibitors of metalloproteinases caused by enhanced expression of CD147 eventually leads to joint destruction in RA [ 26- 28].
Further, Sunde and colleagues found a significant correlation between gene copy number and EVI1 gene expression, and suggested that enhanced expression of EVI1 can partly be explained by increased gene copy number [ 31].
In this study, the identification of hypomethylation and enhanced expression of the three snoRNAs suggest a potential relationship between cancer and dysregulation of snoRNAs.
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