After processing the raw data of microarray datasets, the normalization procedure was executed to avoid systematic biases arising from the variation between different trials (GEO series/GSEs) and samples.
Second, qMRI biomarkers must be standardized to facilitate comparison of response data within a clinical trial, between different sites in a multicenter trial, and between different trials.
The level of immobilization of the rhinoceros also did not differ significantly between different trials.
Median survival rates vary between different trials depending on their selection criteria between 7 and 12 month, while 1 year overall survival is between 30%and45%5% [ 18].
Comparison of the level of antigen specific antibody responses between different trials based on CSP vaccine is difficult in the absence of comparison of sporozoite antibody titers.
When making indirect comparisons of treatment effect between different trials use of a common comparator, often a placebo, is ideal.
While a number of teams determined the reliability of their tests through pilot versions or other means, the inconsistency between different trials still precludes an accurate comparison.
The COG system (Table 1) has the advantage that it is well established, but it includes a treatment variable, extent of resection, which makes comparison between different trials difficult.
