Sentence examples for between different signalling pathways from inspiring English sources

Signal transduction is better understood, but remains complex because of the crosstalk between different signalling pathways [ 15].

Epidermal lineage commitment and morphogenesis are controlled throughout embryonic development and adulthood by an orchestrated interplay between different signalling pathways (Blanpain and Fuchs, 2006, 2009).

Current drug development work recognises that the growth of tumours involves cross-talk between different signalling pathways, and that resistance develops to agents that have a single target.

It is well established that the activation of invader-specific responses in plants attacked by insects is mediated by cross-talk between different signalling pathways [ 38].

Trans-acting modules are predicted to require high physicochemical specificity between them in order to avoid unwanted cross-talk between different signalling pathways comprising conserved domains.

The regulation of genes involved in temperature, drought and salt stresses is known to reflect the cross-talk between different signalling pathways [ 16].

The molecular mechanisms leading to MAPK activation via the production of UV-induced reactive oxygen species (ROS) are not fully understood and may involve interactions between different signalling pathway intermediates.

Recently, RNA-seq analysis has been widely used to elucidate the underlying molecular mechanisms of plant stress resistance and the crosstalk that occurs between different signaling pathways (Mochida and Shinozaki 2011; AbuQamar et al. 2016; Nasr Esfahani et al. 2017).

There are also many examples of crosstalk, the sharing of signal components between different signaling pathways, and recently an edge Ontology has been put forth as a platform to examine crosstalk [25].

There can also be competition between different signaling pathways for β-catenin interactions, such as FoxO and TCF, resulting in transactivation of different genes ([43] and reviewed in [35], [44]).

While the knowledge gained from investigating individual pathways is sometimes critical in elucidating clinically relevant biology, breast cancer represents a very heterogeneous disease, the complexity of which may only be dissected by evaluating the oncogenic cooperation that exists between different signaling pathways.