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There are several differences between different mouse strains and it needs to be verified if observation from the murine system can be extrapolated to humans.
The assessment of strain and sex differences between different mouse strains is greatly facilitated through searchable online strain phenotypic characteristic databases and simple push-button statistical analysis tools, such as those provided in the Mouse Phenome Database [ 200] http://www.jax.org/phenome.org/phenome
Nevertheless, disparate studies suggest that similar differences may exist between different mouse strains as well.
Differences in survival between different mouse strains and treatments were analyzed using the log rank test and Kaplan-Meier analysis.
What is more, there are significant differences in the cardiac function between different mouse strains [ 13].
Unlike the human genome in which sequence differences among individuals are rather limited, the sequence divergence between different mouse strains could be substantial.
Similar(44)
The same study used the high throughput possible with HREM to identify a significant difference in frequency of malformation between different mouse strain backgrounds.
The scores plots of PC1 versus PC2 and PC1 versus PC3 were inspected for differences between the different mouse strains.
The Student's t-test was also used to analyze differences in cytokine concentration in lung homogenates between the different mouse strains or between HK213-infected and mock-infected samples.
The reason for the observed difference in susceptibility between the different mouse strains after intranasal inoculation is not known.
The absence of difference in lipid levels between the different mouse strains on the same diets (results S1) confirms the likely effect of IL-1 inhibition on atherogenesis being a ROS/NO-based mechanism.
More suggestions(15)
between different rice strains
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