Sentence examples for between different iPSC lines from inspiring English sources

Therefore, it is likely that cellular phenotypes between different iPSC lines are likely driven by different genetic backgrounds rather than donor tissue or reprogramming method.

However, differentiation of RPE cells from iPSCs is inefficient, time-consuming, and variable among different iPSC lines (Buchholz et al., 2009).

The repeat lengths varied among different iPSC lines and changed during neuronal differentiation of a given iPSC line.

One of the greatest challenges facing the iPSC modeling field is the enormous variability of different iPSC lines and the neurons derived from them.

Tooth-like structures were recovered from these recombinants in 3 weeks with success rate up to 30% for 8 different iPSC lines, comparable to H1 hESC.

Do motor neurons produced from several different iPSC lines, all from the same patient, have the same response to potential drugs?

Furthermore, the commonly observed variability in the level of neuronal differentiation of different iPSC lines could be prevented with this single-step conversion method.

11, 12, 29, 30 It was further supported by demonstrating telomere elongation, 31 mitochondria rejuvenation up to the state characteristic of the embryonic stem cells, 32 and enhanced DNA reparation capacity 33, 34 in iPSCs, though in different iPSC lines these changes may be pronounced to a varying extent.

These disparities are likely to represent epigenetic differences between individual iPSC lines and highlight the importance of organ-specific iPSCs for tissue-specific studies.

SNPs were not favored in this situation as they would result in variation of CRISPR cleavage activities between iPSC lines derived from different patients.

Regardless of the underlying sources of variation, understanding epigenetic differences between hESC and iPSC lines will be essential for harnessing the potential of these cells in regenerative medicine.