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This higher statistical power garnered could in turn be used to substantially shorten the total acquisition time (making clinical applications more feasible) and/or increase the spatial resolution (allowing finer distinctions between different functional regions).
Nevertheless, our inference is unbiased because instead of relying on the absolute values of polymorphism, we compared polymorphism between different functional regions of the gene that have the same probability to include a PCR error once differences in sequence length were accommodated (below).
Comparisons between different functional regions of a gene (defined below) and synonymous vs. non-synonymous mutations provide robust evidence for selection and avoid confounding effects of population demography, inversion, introgression, and PCR errors because they affect all regions of the gene equally.
Another aspect to address will be the degree of spatial overlap between different functional regions created by the stable binding and local concentrations of different classes of TFs.
The 3-D reconstruction of the collective focal projections and the dual cortical injections demonstrated both potential convergence and segregation in the striatum among the focal terminal fields arising both within and between different functional regions of cortex.
A commonplace analysis in high-throughput DNA methylation studies is the comparison of methylation extent between different functional regions, computed by averaging methylation states within region types and then comparing averages between regions.
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Second, there is some convergence between terminal fields from different functional regions of the prefrontal cortex.
The maps of the diffuse and focal projections from different functional regions were then joined together to determine the extent of potential interaction between different corticostriatal pathways.
Evolutionary patterns in different functional regions are known to be significantly different.
Yet, the susceptibility of spines to the various toxic insults due to the overexpression of APP and its cleavage products may differ between brain regions, between different functional locations within a neuron (e.g. between apical and basal dendrites) or with the age of the experimental animals.
A Product Manager provides cross-functional leadership and bridges organizational gaps between different functional groups, most often between engineering, marketing, sales, and support.
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