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In consequence, no statistical analysis of differences between different doses of a particular statin, or between different statins, was possible.
For NSAIDs there are large differences between drugs and between different doses of the same drug in terms of upper gastrointestinal bleeding.
There was no significant difference in survival between the two treatment groups (P = 0.42) or between different doses of cimetidine tablets (P = 0.46).
There have been many positive studies across various chronic pain syndromes, showing benefit of THC in trials with smoked or vaporized cannabis comparing between different doses of THC, with benefit often noted at higher percentages [28, 47, 157 169].
Levels of pain relief of 50% and above discriminated best between different doses of etoricoxib.
In scenario 2, we hypothesised that a sponsor would favour its own drug in placebo controlled or active comparator trials of statins, but that it would not differentiate between different doses of its own drug in dose comparator trials.
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Considering that there was no difference between the different doses of tumor cells regarding the tumor characteristics, the figures represent the dose of the 10 Ehrlich tumor cells that was used in most of the evaluations– 2(h)).
NT treatment did not change the viability of macrophages under hyperglycemic conditions either in the absence or presence of LPS and 1(b), resp .. Since no major differences were observed between the different doses of NT used (10, 50, or 100 nM), the following experiments were performed using 10 nM of NT.
The dose-intervals between the different doses of isometheptene (racemate and enantiomers) ranged between 5 and 15 min, as in each case we waited with the administration of the next dose until heart rate and diastolic blood pressure had returned to baseline values.
Moreover, the cumulative dose-response curves to DHE were completed in about 50 min, and the intervals between the different doses of DHE (given in volumes of 1 ml/kg each) ranged between 4 and 7 min (as in each case we waited until the vasopressor response to the previous dose of DHE had reached a plateau).
In the pharmacy domain, Healthcare Common Procedure Coding System [ 24] (HCPCS) is also used for coding certain medication data in the financial system, although HCPCS codes may not be available for all medications, and are not granular enough to distinguish between different doses, routes and forms of a given drug, making them also unsuitable for clinical care and research.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com