On the other hand, tri-methylation of histone 3's lysine 27, in addition to differences between genes, also shows differences between different cell lines.
Student's t-test was used to analyse differences between different cell lines.
Future experiments are also needed to determine whether the observed differences between different cell lines are limited only to nonsegmented negative-strand RNA viruses by analyzing effect of RBV on replication of positive-strand RNA or segmented negative-strand RNA viruses in these cell lines.
Moreover, the generation of NO by JS-K largely depends on the intracellular GST-activity that differs between different cell lines or cell types.
Of the 22,283 genes on the Affymetrix 133A chip, ~5800 genes were identified where expression patterns differed between different cell lines both in 2D and 3D, and ~2000 genes were identified where expression differed between the non-malignant and malignant cell lines.
A difference in susceptibility between different cell lines was also observed [25] [27].
Only marginal differences were observed between different cell lines, indicating that genetic elements or the epigenetic status of the mini-EBV genome might influence the initiation pattern.
Experiments in additional hPSC lines verified that our monolayer differentiation protocol, consisting of BMP4/GSK-3βI administration in phase 1 and VEGF-A/DAPT administration in phase 2, resulted in robust endothelial differentiation with minimal differences in efficiency between different cell lines that did not reach statistical significance (Supplementary information, Figure S2F).
Variation in cell fate was observed both as a difference in individual cell behavior within a clonal population (intra-cell line variation) and also as a difference in average behavior between different cell lines (inter-cell line variation) (Fig. 1A).
The difference in the measurements between different cell lines can therefore be attributed to cell attachment and adhesion to the substrate (Wegener et al., 2000).
