Using area-under-the-curve analysis, assuming linear interpolation between consecutive time-points, EQ-5D responses were used to generate quality-adjusted life years (QALYs).
It is determined by summing the mean value between consecutive time points multiplied by the period of time between consecutive time points and then dividing by the total time (see Figure 1).
In one study [ 2] hyperoxia was defined on the basis of a time-weighted SpO2 >98%; this parameter was calculated as the mean SpO2 between consecutive time points multiplied by the period of time between these time points, with the sum of such time-weighted values being divided by total time to obtain a time-weighted average.
Based on either a high number of selected probes per pathway or apparent changes in the number of selected probes from contrasts between consecutive time points or between genotypes at each time point, the top thirteen metabolic pathways were emphasized in this study.
The point prevalence of significant depression and significant anxiety in all women was compared between consecutive time points using z-tests.
The exponential covariance-variance matrix allows for non-equidistances between consecutive time points; the matrix has two parameters: a shared variance and a correlation which would be raised to the difference between any two time points.
Specifically, the projective transformation relating the road plane between consecutive time points is instantaneously derived and filtered temporally based on a data estimation framework using a Kalman filter.
In this work, we adapted the TC method by calculating the correlation coefficient from the change rates rather than change levels between consecutive time points since the time interval of the measurements was not constant (personal communication, Feng He).
We constructed networks between gene ontology biological process categories, which were enriched in differential expressed genes between consecutive time points and different conditions.
In our study, we measured changes in gene expression between consecutive time points, specifically between 10 to 20, 20 to 40 and 40 to 60 DAA.
Differential expression analyses performed between consecutive time points indicated that major transcriptional changes were associated to para/endodormancy, endo/ecodormancy and ecodormancy/bud break transitions.
