Your English writing platform
Free sign upSuggestions(5)
Exact(11)
However, the behavior of QRNA may still be different between coding regions and non-RNA, non-coding genomic regions as coding sequence evolves in a very specific way.
This positive correlation may be the consequence of many factors notably the correlated genealogies existing between coding regions and their surrounding non-coding regions.
The regulatory connections are therefore not specified directly, but rather are an upshot of the correspondence between coding regions and regulatory regions.
In order to further characterize the relationship between coding regions and untranslated regions in human mRNAs, we calculated the correlations between ORF and UTR length, 5'-UTR and 3'-UTR length, 5'-UTR and ORF length, and 3'-UTR and ORF length (Table 4).
Little difference between coding regions and IGRs was observed.
Overlap between UTRs is preferentially retained in all organisms, while the overlap between coding regions and introns is common in zebrafish, drosophila and worm.
Similar(49)
The differences between coding region and intron GC-content are described in several eudicot and monocot species (Goodall and Filipowicz 1991; Carels and Bernardi 2000).
In contrast to the colinearity hypothesis that a continuous nucleic acid sequence generated an amino acid chain, it became apparent that stretches of DNA were often split between coding regions (exons) and non-coding regions (introns).
The divergence between coding regions in Tamias and in U. beldingi, a close relative to I. tridecemlineatus, is around 5%. Non-coding regions are expected to be less conserved than protein-coding regions on average.
The high degree of sequence conservation between coding regions in fish and mammals can be exploited to identify genes in mammalian genomes by comparison with the sequence of similar genes in fish.
With the threshold of allowing maximum 2 mismatches for RNA-seq mapping, this would mean little cross-species mappable reads if the differences between coding regions of human and mouse were distributed evenly.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com