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We also assumed a minimal lag time between changes in risk factors and changes in mortality.
62 63 The time lag between changes in risk factors and changes in CHD mortality is now understood to be relatively short.
In addition, more research is needed to determine the relationship between changes in risk of cardiovascular disease and changes in diet among Arctic indigenous populations (1).
For example, the time lag between changes in risk factor status and observed changes in risk may be related to the assumed risk factor mechanism.
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This study sought to examine the nature of dynamic risk in a sample of mentally disordered offenders by tracking changes in risk over time in the overall group and by examining the relationship between change in risk factors and the occurrence of violence.
To explore potential relationships further, we examined correlations between changes in T2DM risk factors and psychological factors within the yoga group.
Pearson correlation coefficients were computed to examine relationships between changes in cardiometabolic risk markers and changes in fasting plasma insulin, fasting plasma FFA, FFA-RI, ISI FFA-OGTT, and ISI FFA-OLTT.
The strongest associations between changes in weight and risk factors were seen for measures of glycemic control, and clinically significant improvements were observed with just a 2 to <5% reduction in initial weight.
The case-control design for our pathology data, with matching on diagnosis year, prevented us from directly examining the association between changes in histopathology and risk of recurrence over time.
Independent relationships between adverse longitudinal changes in risk variables since childhood and adult pre-diabetes and diabetes conditions were determined in the multivariate models, presented in Table 2. Adverse changes in LDL cholesterol and glucose were independently associated with pre-diabetes status and adverse changes in BMI, HDL cholesterol, and glucose with diabetes status.
No associations were seen between change in CVD risk factors and macrovascular endothelium-dependent and -independent function at any time point.
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