Cytoprotection by lithium and valproate varies between cell types and cellular stresses.
Biological differences between cell types and developmental processes are characterised by differences in gene expression profiles.
Although MHC I is expressed on all nucleated cells, the level of MHC I expression differed greatly between cell types and corresponded to BNP Ab binding (Figs 5 and 7).
Unsupervised classification of the cells indicates differential expression of 'housekeeping' genes between cell types, and re-mapping of two sub-classes of Club cells highlights their segregated spatial domains in terminal airways.
Our findings support a model in which sensory neurons express overlapping subsets of tubulin genes whose functional redundancy varies between cell types and in vivo and in vitro contexts.
The realization that nuclear distribution of DNA, RNA, and proteins differs between cell types and developmental stages suggests that nuclear organization serves regulatory functions.
We demonstrate that enhancer activation depends on cis-regulatory motif combinations that differ between cell types and can predict cell-type-specific ecdysone targeting.
To address the resultant deluge of knowledge and to establish a foundation for systematic reasoning over the immune system inter-cellular network we built immuneXpresso, the first comprehensive high-resolution searchable repository of interactions between cell types and regulatory molecules identified from natural language processing of PubMed abstracts.
We conclude that in contrary to the B-tether, the A-tether has a more intricate composition and consists of multiple components that presumably vary, at differing degrees of redundancy, between cell types and differentiation stages.
