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No heterogeneity between cardiac dysfunction and particular causes of brain death was observed.The frequency of cardiac dysfunction in children with brain death is high.
Furthermore, we did not find a link between cardiac dysfunction and oxidative stress after acute administration of DL-Hcy TLHC.
It is possible that impaired microvascular function contributes to explain the link between cardiac dysfunction and the impairment inVO2peak.
As described in the result section, we only found a simple association between cardiac dysfunction and catecholamine levels in univariate analysis.
While our data must be interpreted cautiously because they are of a cross-sectional nature, our findings are consistent with those of Wiese et al. showing a relation between cardiac dysfunction and development of refractory ascites [ 12].
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This study identified a temporal association between cardiac dysfunction detected by SE and cardiomyocyte oxidative stress.
Recently, van der Bilt et al. studied the relationship between cardiac dysfunction after aneurysmal SAH and neurological outcome.
The relationship between obestatin, cardiac dysfunction and diabetes might confirm its protective role on the cardiovascular system and the negative influence on metabolic control [ 34, 35].
While the link between cardiac dysfunction, specifically the alteration of cardiac metabolism, and deregulated hepatic lipid metabolism is interesting, the mechanisms regulating this crosstalk are not resolved by the work of Magida and Leinwand (2014).
We examined for heterogeneity between cardiac dysfunction with respect to cause of brain death.We identified 60 potential pediatric cardiac donors (age ≤ 18 yr) with at least one transthoracic echocardiogram following brain death.
We aimed to determine the associations between the observed transient cardiac dysfunction and biochemical evidence of cardiac injury in amateur participants in endurance sports and to elicit the risk factors for the observed injury and dysfunction.
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