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The results have been conflicting as Aβ present in plasma is also derived from peripheral tissues, non-neural systems and blood components, thus constantly allowing dynamic interchange of Aβ between brain and periphery.
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This suggests a link between the brain and periphery in the onset and development of the disease.
Our results identify specific responses in the brain and periphery that involve Crhr2.
Receptors, transporters and enzymes are the key molecular mediators that regulate and maintain serotonin levels in the brain and periphery.
It is not an idiopathic reaction and occurs due to excess serotonin activity in the brain and periphery.
All these compounds augment monoamine transmission in the brain and periphery.
Sp1 was abnormally expressed in schizophrenia in both brain and periphery.
Nr4a1 promoter driven eGFP expression was observed in distinct cell populations throughout the brain and periphery (Figs. S1 and S2).
The similarity between the brain and visceral fat with respect to IgG infiltration indicates a common drug target in both the brain and periphery; however, the different IgG subtypes detected suggest that different inflammatory responses might occur in each tissue.
The coronary patients were younger for first-ever and recurrent admissions compared with their brain and periphery counterparts.
Such alterations have been detected in both the brain and periphery, and are present in first- onset drug-naïve patients.
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