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However, prospective studies are required to elucidate the mechanism and to understand the relative importance between brain and peripheral insulin resistance.
The differences between brain and peripheral tissues are, on the other hand, striking.
A reverse pattern of differential concentrations of biomolecules between brain and peripheral blood samples has sometimes been observed.
Set one sampled for comparison of gene expression between brain and peripheral blood, was collected from 12 male vervets, aged ∼3 years at the time of sample collection.
How these peripheral effects may impact the risk association of apoE with AD is unknown, and it is important to note that there is little interaction between brain and peripheral cholesterol metabolism [ 14].
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The compound exhibited high peripheral and adequate brain levels upon oral dosing in rodents.
Recently, Rollins et al. [ 25] demonstrated considerable overlap between gene expression in brain and peripheral blood, from the same individual, using two independent populations and different high-throughput array platforms.
By sending signals back and forth between the brain and peripheral organs, these receptors control how many calories the body wants to take in.
Although the brain is often referred to as an "immune privileged" site, there is increasing awareness of the significant communication between the brain and peripheral immune system.
Second, the potential for freezing to induce nociceptive signals will be greater for larger animals, which can maintain greater thermal differentials between the brain and peripheral tissues (Key, 2015), and have higher crystallisation temperatures (Lee and Costanzo, 1998).
Hence, we expect that the structure of the propeptides may differ between the brain and peripheral cells, as each serves a different need: neurons need to synthesize large quantities of the mature peptide, while in the periphery the propeptide reflects the phenotypic state of the signaling cell.
More suggestions(13)
between brain and brawn
between brain and other
between periphery and peripheral
between brain and systemic
between centre and peripheral
between brain and spinal
between brain and skull
between depression and peripheral
between dementia and peripheral
between memory and peripheral
between liver and peripheral
between core and peripheral
between brain and periphery
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