We found that when the spacing between time constants was too small, on different fits neighboring moduli were traded off against each other, so that when one was high the other was low, and vice versa.
No significant differences were found between the respective time constants of the fast components of burst distributions.
Importantly, there was no significant difference between the decay time constants of the events recorded from neurons expressing GIT1 RNAi, βPIX RNAi, or PAK-AID compared with control neurons, indicating that the receptor properties are unaltered.
The link between decay time constant and spike timing precision seems to be via the time span the membrane potential spends close to or at the spike threshold level.
The largest difference between unfiltered and filtered data, as well as between the different filter time constants, was found during nighttime.
Detailed relationship between relaxation strength and time constants has been derived for some of the secondary motions.
For higher northern latitudes, compared with south orientation, useful solar absorption differs by about 2%, 4% and 6% between large and small time constants for east, west and north orientations, respectively.
Taken together, our results indicate an inverse relationship between the de-adhesion time constants and cell stiffness, and establish the utility of using trypsin-induced de-adhesion as an effective tool for probing cell contractility.
The influence of three critical design parameters, namely the time constant ratio (ratio between the time constant of the harvesting circuit and the period of the mechanical system), the electromechanical coupling, and the shape of the potential function, on the effective frequency bandwidth is analyzed.
Fig. 4C shows similar data for ET-1, demonstrating little correlation between fade time constant and initial response amplitude (r of 0.09, p of 0.9).
