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There are no overlapping pathways between both modules, suggesting that the MYC module and the core module are indeed involved in very different pathway patterns in regulating pluripotency and self-renewal of ES cells.
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More links were found in hub genes between modules 1 and 3 than between any other modules, suggesting that the genes in these two modules act in a more coordinate fashion.
Our results regarding the changing expression patterns of cell type-specific modules suggest that both neurons and glia are affected by AD progression.
This network module suggests a relation between FFA, interacting partners of proto-oncogenes like c-Fos and c-Jun, transcription factor GCR, ATP dependent chromatin remodeling factor SMAD3 and their interaction with TGFB and MAPK pathways.
The fact that these two processes are present in the same module suggests a strong relationship between them – immune response can be an outcome of oxidative stress but also oxidative stress can be an outcome of immune response [ 41] and considering that, we will further discuss other possible causes of inflammation in liver.
There were only three overlapping genes between both modules, again showing that both modules were functionally separate.
Moreover, the crystal structures revealed a tight interaction between both modules, which are further stabilized by a zinc finger.
In order to determine the overlaps between the modules we suggest to use one of the local maxima based methods.
We did not find a significant correlation between mean cyclical EFM length and module size, suggesting that larger modules may not necessarily possess longer cyclical EFMs.
Furthermore, we found no difference in pretest scores between the control courses and module courses, suggesting that the populations were relatively similar before instruction.
We did not find any significant differences in the outcome between the two treatments (Table 6), suggesting that both modules are equally effective for student learning of key concepts.
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