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Feedback takes place between both models at each time-step.
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To evaluate the significance of the AICs' difference, we calculated a chi-square (difference between -2log likelihood of both models) at a degree of freedom (difference between degrees of freedom of both models).
Further comparisons between both models for heterogeneous conditions at the tissue level are shown in the next sections.
Multiscale modeling, besides modeling the system, needs to address the issue of how to bridge the gaps between different methodologies and between models at different scales.
Results show good agreement between the models at low loadings and kinetic parameters are provided for all models.
Our procedure is adaptive in an unusually strong sense, permitting the analyst to use any statistical or machine learning method she chooses to estimate the optimal threshold, and to switch between different models at each iteration as information accrues.
It briefly explores how the nature of the information flow between the models at the different scales is influenced by the choice of framework, and presents some restrictions on model framework compatibility.
Although there were some differences between the models at the amino and carboxyl-termini, the region for residues 2364 2480 were consistent with each other using the different proteins as models for the LRRK2 WD40.
The microheater operates at overall heat transfer coefficients of ∼600 1000 W m−2 K−1, and it enabled to distinguish between different kinetic models at a given temperature.
Numerical calculations indicated substantial differences between the two models at low frequencies due to higher order terms omitted in the RC model.
However, most of these models address the frequency and severity independently, and miss the correlations between crash frequency models at different crash severity levels.
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