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We measured de novo synthesis of free cholesterol by evaluating incorporation of 3H-mevalonolactone into free cholesterol over 16 h and incorporation of 3H-oleate into cholesteryl-ester over 4 h and found no difference between both experimental groups (data not shown).
The unpaired Student's t-test was used for establishing statistical significance (P < 0.05) between both experimental groups.
We calculated absolute differences between non-papain-injected and papain-injected joints and compared these values between both experimental groups.
Animals in both groups received 55 ± 2 MBq (mean ± SD) of [In]-DOTA-Bz-folate; no significant difference was found between both experimental groups.
Relying on the normalized gene signals, the average log2 fold-changes between both experimental groups (tebuconazole-treated vs. untreated) were assessed for each gene.
Based on the processed, normalized gene signals the average log2 fold-change (log2 FC) between both experimental groups (tebuconazole treated vs. untreated control) was assessed for each gene (Additional file 3).
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The frequency of training was three times a week, with at least 1 day of rest between sessions in both experimental groups.
The distance between magnets decreased in both experimental groups.
In the retrosplenial area of the neocortex there was a significant overall difference in AT8 immunolabelling for tau between the experimental groups, both when considering average intensity of labelling (P < 0.01 by analysis of variance; Figure 2A) and labelled area (P < 0.01; Figure 2B).
Significant differences were found between the individual experimental groups both before [ F 3.25) = 10.32; P < 0.001] and after captopril ingestion [ F 3.25) = 13.47; P < 0.001].
The use of the hierarchical statistical model yielded estimates of both variability between experimental groups and uncertainty in TCE toxicokinetics.
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