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The behavior's differences between both classes of systems are studied to determine the best way to adapt these concepts to this new environment.
Here, we study the formal relationship between both classes of models and show that when the source nodes variables are observed, RNNs can be viewed as limits, both in distribution and probability, of BNs with local conditional distributions that have vanishing covariance matrices and converge to delta functions.
Cheminformatic analysis of the frequency of selected structural elements occurring in natural products in comparison to compounds of synthetic origin should gain more insight in essential differences between both classes of compounds.
These differences between both classes of estimators are not completely unexpected.
Reviewer 1: The authors make a detailed comparison between both classes of networks and the key dynamical features shared by both.
Negative feedback between both classes of transcription factors maintains the cells in an undifferentiated state, whereas an imbalance leads to differentiation (Takada et al. 2009).
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The Class I gene, Rps1-k-3, showed a recombination breakpoint at the 3' untranslated region originating from sequence exchange between members of both classes of genes [ 1].
Many features are shared between lncRNAs and mRNAs; both classes of RNA possess 5′-methylguanosine caps (Neil et al., 2009) and poly(A) tails (David et al., 2006) and have broadly similar lengths.
Those differences were due to the statistical strong differences sustained, for both features, between classes of grade I and grade III, while there were no statistical differences found between the other classes.
Having obtained a picture of an "average" mRNP, we next investigated how RNP composition varies between mRNAs and between classes of Pol II transcripts.
Both pro-apoptotic (e.g. BAK, BAX, BID, BIM, NOXA, HRK, PUMA, BAD) and anti-apoptotic (e.g. BCL-xL, BCL-2, BCL-w, MCL-1, A1) members of the BCL-2 family participate in a complex network of PPIs.[ 384, 385] Interactions between members of both classes are involved in the sensing of cellular stress, thereby modulating apoptotic pathways.
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