Sentence examples for between binding affinity and from inspiring English sources

This correlation between binding affinity and cleavage efficiency contrasts with RuvC, which binds equally well to intact and nicked HJs (with and without a 5' phosphate at the nick site) even though optimal cleavage of a nicked HJ depends on the presence of a 5' phosphate at the nick site.

A correlation between binding affinity and biological activity was found, albeit not across the whole range of affinities.

Therefore, when comparing immunotoxins in which scFvs from different antibodies are fused to the same toxin domain (DT or PE) a broad correlation appears to exist between binding affinity and immunotoxin potency.

A direct correlation exists between binding affinity and toxicity (Opota et al. 2008).

Further studies in the binding kinetics of h357 IgG need to be conducted to elucidate the correlation between binding affinity and bioactivity.

Thus, our data do not support a simple, linear correlation between binding affinity and the pH threshold of pore formation in the relationship between TEM8 and PA.

A detailed analysis on protein expression levels for these peroxisomal proteins revealed a remarkable negative correlation between binding affinities and expression levels of cargo proteins, thus providing a mechanistic framework to generating a uniform population of Pex5p-cargo complexes necessary for proper peroxisomal biogenesis [ 28].

The dissociation between binding affinity, potency and efficacy for the opioids among these variants may provide insights into the wide range of opioid responses among these agents observed clinically and opens new avenues in designing selective drugs based upon their efficacy and potency rather simple binding affinity.

While different PL9-11 isotypes have the same initial attack sites within the ALWPPNLHAWVP peptide, there was no correlation between binding affinity to the peptide and proteolysis rates.

The antibody assay used was a highly sensitive assay in which a relatively small difference between binding affinity of the pretreatment and post-treatment sample could lead to a statistically significant increased binding to corifollitropin alfa.

In this context, in this study, the correlation between heparin binding affinity and cell proliferation activity of hFGF1 is examined by extending the heparin binding pocket through selective engineering via charge reversal mutations (D82R, D84R and D82R/D84R).