Sentence examples for between binding affinities and from inspiring English sources
A detailed analysis on protein expression levels for these peroxisomal proteins revealed a remarkable negative correlation between binding affinities and expression levels of cargo proteins, thus providing a mechanistic framework to generating a uniform population of Pex5p-cargo complexes necessary for proper peroxisomal biogenesis [ 28].
This correlation between binding affinity and cleavage efficiency contrasts with RuvC, which binds equally well to intact and nicked HJs (with and without a 5' phosphate at the nick site) even though optimal cleavage of a nicked HJ depends on the presence of a 5' phosphate at the nick site.
A direct correlation exists between binding affinity and toxicity (Opota et al. 2008).
A correlation between binding affinity and biological activity was found, albeit not across the whole range of affinities.
Therefore, when comparing immunotoxins in which scFvs from different antibodies are fused to the same toxin domain (DT or PE) a broad correlation appears to exist between binding affinity and immunotoxin potency.
Further studies in the binding kinetics of h357 IgG need to be conducted to elucidate the correlation between binding affinity and bioactivity.
Thus, our data do not support a simple, linear correlation between binding affinity and the pH threshold of pore formation in the relationship between TEM8 and PA.
This study demonstrates a possible correlation between binding affinity and tumour residence time when examined in this model.
These results (1) further confirm the important role of ClfA in virulence and (2) underscore the important distinction between binding affinity and functional activity.
An alternative explanation might involve complex tradeoffs between binding affinity and specificity (Havranek et al. 2004; Ashworth and Baker 2009) that could be elucidated using recently developed high-throughput approaches (Zhao and Meng 2009; Nutiu et al. 2011; Pollock et al. 2011).
Direct comparison between binding affinities of DNA/DNA and RNA/DNA duplexes shows, that RNA/DNA purine-purine MMs are more discriminating than corresponding DNA/DNA MMs.
