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Yet the cost of funding a breakthrough drug is rising by 13.4percentt annually.[2] For the past few years, a group of scientists, researchers and philanthropists has been working to bridge the gap between basic research and patient care (known as "translational medicine").
"This is the link between basic research and actual patient populations," Dr. Langston said.
"The reason is that the gap between basic research and commercialization has been dramatically reduced by genetic engineering tools".
"They could easily restore the balance between basic research and development activities," he said.
Translational research provides a bridge between basic research and clinical practice.
In 2003, he was lured by Michael R. Milken to start FasterCures, a charity intended to speed the translation between basic research and lifesaving medicines.
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Between 2006 and 2011, NCRR selected between five and 12 centers per year to receive at least $20 million over 5 years to build partnerships between basic research scientists and clinical scientists and promote the translation of research findings into clinical applications.
A fundamental underlying principle has also been to link research with innovation, in a way that reduces the distance between basic research, applications, and products.
Another example in which ontologies will increasingly be applied is to bridge the gap between basic research results and clinical applications.
Translational research, as a whole, aims to bridge the gap between basic research, applied clinical research, and clinical practice (figure 1).
Within the frame of linear innovation, there is a sequential 'first-then' relationship between basic research (knowledge production) and innovation (knowledge application).
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