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This conclusion is consistent with selection maintaining the arrangement polymorphism due to fitness benefits conferred by coadapted gene complexes, which are maintained by suppressed recombination between arrangements.
Under this model, natural selection maintains favorable combinations of alleles within and between arrangements within populations, and suppressed recombination in arrangement heterozygotes prevents the breakup of coadapted alleles within arrangements [8] [12].
Exchange between arrangements in populations with a high frequency of fused X chromosomes creates a gradient of sex linkage along Chromosome 4. Reduction in diversity on the unfused arrangement through drift, background selection or selective sweeps should be greatest in proximal chromosomal regions within northern populations.
Furthermore, a high amount of correlation exists between average Fop values for each gene between arrangements.
This finding suggests that genetic exchange and recombination still occurs freely outside of inversions between arrangements.
The extent of LD between markers and the inversion was also much lower in the simulated data than was observed, even when the level of gene exchange between arrangements was low, except when the starting divergences between arrangements were extreme.
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For me, it's not as clean and pure when I take time in-between arrangements - it starts to sound scattered.
Population cage experiments indicate that there are fitness differences between arrangement genotypes [7], [8].
The relationship between arrangement and expression has not been systematically characterized within heterologous modules to date.
Chromosomal inversions are known to suppress recombination between arrangement heterokaryotopes (Sturtevant and Beadle 1936; Andolfatto et al. 2001).
Mean estimates of heterozygosity in the three regions within- and between-gene arrangements are shown in Table 1.
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