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This architecture implies this protein might provide a unique tool for further investigations into the relationships between architecture and function of pattern recognition proteins.
These can be used to perform in silico simulations to promote unravelling the relation between architecture and function as below illustrated for liver regeneration, and bridging from the in vitro situation and animal models to humans.
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Microscopies based on focused electron probes allow the cell biologist to image the 3D ultrastructure of eukaryotic cells and tissues extending over large volumes, thus providing new insight into the relationship between cellular architecture and function of organelles.
This approach can be applied to further understand the regulation of assembly and remodeling of septin higher-order structures, as well as the relationship between septin architecture and function.
Unfortunately, we still lack an accurate view of the relationship between the architecture and functioning of ecological networks.
This enables simulation and analysis of the interactions between plant architecture and functioning.
Not surprisingly, islet architecture and function are dissimilar between humans and typically studied model organisms, such as rodents and zebrafish.
The maintenance of normal joint architecture and function requires equilibrium between the synthesis and degradation of the specialized extracellular matrices that make up bone, cartilage, and tendons.
When the ligament is damaged the synergy between the bone and tooth is lost and tissue architecture and function becomes significantly disrupted [1].
Alternatively, regulated periods of imbalances between turnover events (proliferation, differentiation and loss) drive developmental and adaptive changes in the epithelial tissue architecture and function.
This substrate accumulation in lysosomes affects the architecture and function of the cells and the tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com