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A summary of the statistical comparison of mutation distributions between all four genotypes is presented in Figure 4F.
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To discriminate between these possibilities, cultures of all four genotypes were exposed to CTX-HRP only during the recovery phase, following a 90 s stimulus, and then analyzed at the 10 and 30 min time points.
As expected, essentially the same metabolites that are responsible for the differences between all three genotypes were with minor differences also significant for discriminating between groups in the two-way comparisons (as shown in Table 4).
A non-Rb regulated gene, p21, showed no difference between all three genotypes.
The incubation period of iatrogenic Creutzfeldt-Jakob disease is significantly different between all three genotypes.
Similarly, for the IH SNPs, there is an expectation of congruence between all three genotypes (the reference and both inbreds).
Furthermore, we have found that the density of α1-adrenoceptors (α1A and α1B) are also similar between all three genotypes (data not shown).
In this study, the class containing SNP variations between all three genotypes and the RA (87) was chosen to mine SNPs for assay development.
From the 1,302 DEG identified in total, 289 were differentially expressed only for CM-82036 compared to 114 DEG, which were shared between all five genotypes.
P-values are for trend between all three genotype groups and pairwise comparisons based on estimated marginal means were adjusted for multiple comparisons with Bonferroni correction.
Analysis of cartilage sequential extractions revealed differences in the extractability of COMP between mice of all three genotypes (Fig. 2B).
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