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The underlying principle guiding their development realizes a tradeoff between a specificity of information granule (which we want to keep as high as possible) and the associated experimental evidence (which needs to be maintained high as well).
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When compared with human double-entry, the software had a sensitivity of between 91 and 97% and a specificity of between 88 and 94%.
The interaction between different scales is a specificity of these systems, since a local perturbation might influence the behavior of the whole core, or a global perturbation can influence the properties of the media on all scales.
The fact that an 8-gene predictor set was able to establish a sensitivity of 83% with a specificity of between 64 and 75% in a blinded set of samples is promising and will need to be validated in a large sample set.
Employment of 16 and 64 slice systems have demonstrated a sensitivity ranging from 83 99% and a specificity of between 93% and 98% [ 47– 51].
Sample size calculation: previous reports of stereoscopic evaluation of the optic nerve head by glaucoma specialists have shown that its sensitivity for the diagnosis of glaucoma ranges between 70 and 80% for a specificity of 80% [ 14– 16].
Furthermore, semiquantitative [18F]fluoroethylcholine uptake in identified lesions is able to discriminate between Gleason >6 CaP with a specificity of 90% and a positive predictive value of 83%, which is an improvement over that of prostate biopsy results when compared to whole mount specimens.
It has a sensitivity that ranges between 33% and 81% and a specificity of 82% 96%.
A cut-off of 13 yielded a sensitivity of 0.77 and a specificity of 0.62 between BP and UP.
With a cut-off value of 4.0 ng/mL, the sensitivity has been reported as being between 67 and 80% but with a specificity of only 20 30% [ 13– 15].
Until recently the sensitivity of CT for identifying Stage II (T3a) tumors has only been between 44 and 50% with a specificity of 90% when all the signs are present.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com