Sentence examples for better tolerability of from inspiring English sources

Applications in man showed, in general, reduced toxicity and better tolerability of administration with not too encouraging efficacy.

Despite the equivalent efficacy and better tolerability of these drugs, more than 25% of patients remain refractory to treatment.

However, because of the comparable efficacy with better tolerability of gemcitabine and cisplatin (GC) in patients with metastatic disease, GC has become the most commonly used regimen in the neoadjuvant setting.

Regardless of severity, better tolerability of antiretroviral regimens is crucial for improving adherence and immunovirologic efficacy.

Recently, clinical studies have shown a better tolerability of never antiepileptic drugs.

Better tolerability of SGAs was considered as one of their major advantages as a class [ 7].

This agent became available on the European market for the treatment of schizophrenia with the promise of a better tolerability because of the absence of those extrapyramidal side effects that afflicted patients treated with other antipsychotic agents (e.g., chlorpromazine and haloperidol, now defined as "typical" or first- generation agents, FGAs) [ 1].

Using the intermittent schedule, the maximum tolerated dose (MTD) was comparable for the two routes (15 mg/kg), but the toxicity profile suggested a better tolerability in terms of lethal effects after oral administration.

For future research it would be necessary to recruit larger numbers of patients on both CBZ and OXC and other AEDs such as lamotrigine, gabapentin and pregablin in order to compare better tolerability especially aspects of cognitive dysfunction in order to provide clinicians with the better guidance on how to troubleshoot drug intolerance.

This may result in better tolerability, namely reduction of gastrointestinal side effects [ 29, 85].

Better tolerability allowed 68% of TD system users to reach the maximum study dose, compared with only 32% of those in the oral OXY arm.