Sentence examples for better tolerability compared with from inspiring English sources

Conclusions: Vildagliptin (50 mg bid) showed superior efficacy and better tolerability compared with voglibose in Japanese patients with T2D.

In two phase 3 trials, micafungin demonstrated non-inferiority to both caspofungin and liposomal amphotericin B for the treatment of invasive candidiasis and candidemia, and showed better tolerability compared with liposomal amphotericin B [ 28, 29].

Pharmacokinetics and pharmacodynamics studies, and recent clinical trials suggest that denosumab might be a promising alternative to bisphosphonates for the treatment of resorption-related hypercalcaemia in patients with renal insufficiency, for a more rapid and sustained effect on bone resorption, and a better tolerability compared with bisphosphonates.

Indeed, NICE guidance in England and Wales recommending the first-line use of atypical antipsychotics to manage schizophrenia in various primary and secondary care settings recognized the overall indirect cost benefits (e.g. more patients living independently and returning to work) and better tolerability compared with typical antipsychotics (NICE 2002a, b).

18– 20 Again, capecitabine completed the same cycle as was done with 5-FU, and it was tested in metastatic settings first where it showed good equivalent efficacy and better tolerability compared with 5-FU, and subsequently also in the adjuvant setting.

Add-on lixisenatide once daily in type 2 diabetes inadequately controlled with metformin demonstrated noninferior improvements in HbA1c, with slightly lower mean weight loss, lower incidence of hypoglycemia, and better gastrointestinal tolerability compared with exenatide twice daily.

A 2007 systematic review of randomized controlled trials (RCTs) showed that selective COX-2 inhibitors (celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) produced significantly fewer ulcers (RR, 0.26; 95% CI, 0.23 to 0.30) and ulcer complications (RR, 0.39; 95% CI, 0.31 to 0.50) as well as better GI tolerability compared with ns-NSAIDs [ 15].

However, s.c. delivery of rIL-2 has improved tolerability compared with c.i.v.v

AIs have also demonstrated significant improvements in tolerability compared with tamoxifen.

8, 13, 25, 31 Lan ATG showed a trend towards an improved digestive tolerability compared with Lan MP.

Prolonged-release formulations of metformin are available, which appear to improve gastrointestinal tolerability compared with the immediate-release formulation [ 58].