"We need measures that are independent of the industry and use a better sample of houses".
Why do we have to look enviously at the front page of Al-Jazeera English for a better sampling of important news stories at any given time?
Such training data, over several days or even longer times, are thus expected to provide a better sampling of RSS fingerprint values.
While the Cα model allows better sampling of the conformation space occupied by the transition state, the all-atom model offers a more detailed description of the structural and energetic properties of the conformations included in the TSE.
Furthermore, the comparison between the Native-Seeded and Omega-Only results also indicates that a better sampling of the ligand conformations, in particular for large, flexible ligands would improve PharmDock's performance for this class of compounds.
Small is beautiful – reducing the size and complexity of chemical starting points for drug design allows better sampling of chemical space, reveals the most energetically important interactions within protein-binding sites and can lead to improvements in the physicochemical properties of the final drug.
The stimuli were repeated 7 times per session to obtain a better sampling of the neural responses.
This potentially indicates the presence of a 'Lagerstätten effect', corresponding to a better sampling of biodiversity in one time bin relative to another (see below).
Finally, it can allow for a better sampling of the population, as it is easier (and probably cheaper) to get a wider coverage of the population's physical effort cost functions than of the monetary cost functions, and can thus offer us a bigger and more representative set of behaviors.
The use of other methods, such as replica exchange simulations or coarse-grained approaches could be explored to provide an additional comparison with the results obtained here, for example to reach a better sampling of structural configurations at long time-scales.
