This study considered four different concentrations, 0, 1, 50, and 100 μg, and indicated better response to the higher concentration range.
The results suggested that free RGO exhibited better response to NH3 and showed higher sensitivity with concentrations at ppm levels compared to those of the RGO attached with acid-doped PANI and de-doped PANI [108].
Clinically, these data relate well to observations that show a better response to BCG treatment of high-grade compared to low-grade tumours (Table 1 > -wrap-foot>) (Melekos et al, 1993).
Additionally, tumor cells expressing hormone receptors presented a better response to hormone therapy and patients demonstrated higher survival, both disease free as overall [ 25, 26], and better prognosis [ 27].
This interesting paper demonstrated a higher sensitivity for primary tumours than for metastatic sites and tumours with high uptake had a better response to chemotherapy than lesions without uptake, suggesting that somatostatin receptor expression may provide useful biological behaviour characterisation.
High perfusion before and during radiotherapy suggests increased vascularity and high tumour oxygenation, both associated with better response to treatment and therefore better prognosis.
Furthermore, in some cases high serum T predicted a better response to therapy [ 43, 48].
Tumours with initially high FLT uptake showed a better response to HILP (r = 0.64, P < 0.05)[ 41 ].
Correspondingly, analysis of the RECIST scores also suggested that patients expressing higher RNF125 levels showed a better response to BRAFi.
Moreover, high levels of AIB1 were associated with better response to the AI examestane (Yamashita et al, 2009).
