Sentence examples for better represent the human from inspiring English sources

These transgenes contain point mutations commonly found in TP53 in human tumors, such as the p53-R172H mutant, which have dominant-negative or gain-of-function properties, and thus in some ways may better represent the human situation than complete absence of gene product [ 26].

Biotech startup Ixchel Scientific hopes to bring higher success rates to trialed cancer drugs using an environment that better represents the human body.

Although it is clear that humans cannot be used as subjects in many experiments, a model which better represents the human response would be a logical step forward.

The HAE model better represents the human airway (compared to cell line models) in that it contains all the functional cell types found in the airway (ciliated, secretory, and basal cells) and more accurately represents the expression pattern of sialic acids found in the upper human respiratory tract [25] [30].

Animal models of uveal melanoma have undergone many improvements, leading to the development of experimental systems that better represent the disease in human beings.

The researchers used mechanically disrupted tonsil explants for these studies, reasoning that these primary human tissues would better represent the complexity of T cell subsets and the cytokine milieu found in vivo (Doitsh et al., 2010).

In comparison to its actual representation, our revised clone alignment clearly better represents the 8p23.1 complexity and improves the human reference sequence as an invaluable resource for the investigation of individual genetic variations.

Whether dirty mouse models represent the human condition better than standard lab mice — and provide a better testing ground for drugs — also remains to be seen.

Specifically, humanized rat models have a more similar Firmicutes:Bacteroidetes ratio to human donors and could represent the human donor better than could germ-free mouse models.

Advantages of a rat versus a mouse model include its size and evidence that the rat model may represent the human disease processes better than the mouse equivalent (Oyasu, 1995).

The new EAE model appeard to lack all the negative aspects of the rhesus monkey EAE models and to represent the human disease multiple sclerosis much better.