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Therefore, the derivatives bearing a relatively small and/or electron donating moieties in phenyl rings, such as methyl and methoxy, displayed better inhibitory activities than derivatives carrying bulky and/or electron withdrawing groups, plausibly due to the better insertion into the active site channel and also more efficient binding interaction with aforementioned aromatic residues.
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Midgut juice treatment after interaction of Cry1Ab toxin with cadherin induces a change in the mass of the oligomers, and these structures show slightly better insertion into synthetic membranes.
Considering both molecules, the difference in their ability to erode the DPPC gel phase domains might be due to a better insertion of the moxifloxacin than the ciprofloxacin into the fluid matrix, and a more marked decrease of the line tension at the boundary of the DOPC/DPPC phases resulting from a fluidification of the DPPC.
To obtain a better insight into the insertion into the different chromosomes we generated 15 'subpopulations' (P1a-P1o) by intravenous injection of 1-5 parasites of parent population P1 in 15 different mice.
The insertion of TE-EK graft was carried out using the EndoGlide insertion technique43 with modifications made to facilitate the graft insertion into the anterior chamber of the rabbit as previously described27.
Mutagenesis by random linker insertion into the lamB gene of Escherichia coli K12.
Rehling, P. et al. Protein insertion into the mitochondrial inner membrane by a twin-pore translocase.
Gilding was sometimes added to portraits after their insertion into the mummy wrapping as a finishing farewell touch.
Mr. Leahy said the House and Senate's insertion into the election would leave the next president "severely damaged throughout his term".
So much for the manipulation of ideas and their insertion into the record.
Monolayer isotherms demonstrated protein insertion into the lipid monolayer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com