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These compounds showed better inhibitory activity against NA.
From the activity assay results, compounds 1 and 2 showed better inhibitory activities against NA.
SiCYS showed a better inhibitory activity of papain than SiCYS-N.
Some of them have better inhibitory activity than the most potent Tofacitinib (CP-690550).
Seven compounds showed better inhibitory activities than the standard Cyclosporin A (CsA).
Especially, compound 9w (IC50 = 85 nM), exhibited better inhibitory effect compared with SAHA (IC50 = 161 nM).
In a previous study from our research group, several extracts derived from P. Cablin have better inhibitory activity on NA.
The results revealed that seven organic compounds displayed better inhibitory effects on the growth of the tested bacterial strains.
In hemagglutination assays, ligands 32A-38AA) showed better inhibitory activities than the standard inhibitor, methyl α-D-mannopyranoside.
The in vitro studies showed that these compounds had better inhibitory properties against Aβ aggregation than curcumin.
Moreover, polymers with benzyl group attached to nitrogen atom showed better inhibitory effect on bacteria and phytopathogenic fungi.
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