Co-localization of the RCM/OCT images, imaging depth, sensitivity decay within the imaging range, field of view (FOV), and imaging resolution were measured.
Moreover, by detecting the significantly less scattered acoustic waves, photoacoustic imaging can achieve better resolution at higher imaging depth in biological tissues [15, 16, 17].
In addition, the calibration mirror image limits imaging depth [ 19].
This provided a much greater focal depth and much better imaging resolution in the elevation direction than can be achieved by using 1D probe.
With these considerations, our system was able to provide a better performance in both the imaging speed and imaging depth, which will be presented further in the later section.
The OCT images typically have deep (2-3 mm) imaging depth with 5-10 μm transverse resolution.
Current imaging tools for in vivo visualization of nailfold capillaries include nailfold capillaroscopy, which however allows for very shallow penetration, whereas with the aid of our system imaging depth can potentially be significantly extended to get a better insight from deeper vessels surrounding the nailfold.
To give a better impression of the intensity fluctuations we segmented the layers IS/OS, OS, ETPR and RPE by summing the pixels over an imaging depth of ~12µm around the center of the peak intensity of each layer (except for the OS layer where the gap between the segmented IS/OS and ETPR layers was integrated).
"You'll get tighter bass, better imaging, more detail," Mr. Bowers said.
Having men cycle on their backs allowed for better imaging, she said.
