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Ideally, the better frailty instrument should have a sensibility and a specificity corresponding to 100%.
During follow-up periods without intensive interventions, most individual stayed at their original status, the chances for natural transition to better frailty status was a lot fewer.
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In order to better define frailty, factor analysis (FA) appropriate for binary data was conducted using the Mplus software (version 4.2).
To better understand frailty in China in relation to deficit accumulation, we analyzed data from the Beijing Longitudinal Study of Aging (BLSA) and compared the results with that in the Western populations.
A paradigm that includes a better understanding of frailty may cause a fundamental shift of focus, with the diagnosis, treatment and prevention of frailty being considered equally as important as acute physiologic support for critical illness.
One strategy is to strive for better measures of frailty for covariate adjustment and for exclusion of patients known to be near death at the outset of the autumn vaccination campaign.
In Europe, the Survey of Health, Aging and Retirement in Europe (SHARE) is a gold mine of individual, economic and health information that can provide insight into better understanding of frailty across diverse population settings.
In our study, subjects in the PST group had better improvement in frailty and PRIME-MD scores than subjects in the non-PST group; but the differences did not reach statistical significance.
For this, clinical studies in elderly and in unfit MDS patients have to be performed as well as basic research to better understand ageing, frailty and their interface with cancer.
The requirement in the 2014 general practice contract for increased identification of vulnerable older members of the practice population may result in better recording of frailty in general practice data and enable more thorough investigation of its effects on hospitalisation in future research.
Previous ages may have wanted flawless heroes (or been fed them by their betters); today, human frailty is what sells.Princess Diana had plenty of that.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com