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To determine if a multi-SNP model could better explain the variability in Lp(a) levels, we performed stepwise linear regression combined with ANOVA (see Methods).
The corresponding loading plots show that motifs that better explain the variability are the same identified in the hierarchical cluster analysis (Figure 7B).
This suggests that there may be a more complex underlying mapping algorithm between EQ-5D-3L, QLQ-C30 and toxicity which might better explain the variability and prediction of EQ-5D-3L, partinularly in patients with 'Poor' health states.
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In contrast, Fogelholm et al. [ 6] found that variance in physical activity better explained the variability in physical fitness (ß-coefficients between −0.33 and 0.49) than that in overweight (ß-coefficients between −0.27 and 0.24).
On the other hand, some authors have suggested that, compared with GDP, more complex constructs such as 'National Intelligence' or the 'K factor' including measures of national IQ; gross national product; life expectancy; birthrates; infant mortality; HIV/AIDS and of rape, serious assault and homicide may better explain the geographic variability of suicide rates.
The effects of developmental and other factors on Ep pharmacokinetics and pharmacodynamics were investigated in order to better explain the observed between-subject variabilities and to ultimately suggest individualized dosage regimens.
No predictors were included to explain the variability in the slope.
The variability of pS6 levels among mice may explain the variability of biological effects of rapamycin.
Also the variability in mammaglobin expression in different breast (cancer) tissues may explain the variability in expression.
Thus, NAAT may not be a satisfactory screening tool for SNPT and further studies should pay attention to the clinical background and several other factors under which NAATs are conducted to better explain such variability.
Uncertainty highlighted in the modeling process suggests that we need a better understanding of the historical ecological dynamics of household institutions and land use change in order to better explain relationships between variability in land use intensity and the fire regime.
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