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The BEDIP-N study also has strong potential to better elucidate the underlying pathophysiological mechanisms of GDM.
A more detailed study, therefore, of additional measures in multiple white matter tracts, in association with a wider range of cognitive functions, could better elucidate the underlying neuropathology of white matter changes in VCFS.
To better elucidate the underlying pathophysiology, we sought to establish a rodent model of the cognitive and neurotoxic effects resulting from direct administration of MTX into the cerebrospinal fluid (CSF).
Thus, to better elucidate the underlying mechanism (s) of Rg1 in age-associated hematopoietic microenvironment degeneration, here we investigated the effects of Rg1 in the BMSCs of a D-gal-induced aged rat model.
Thus, to better elucidate the underlying mechanism (s) of Rg1 in age-associated hematopoietic microenvironment degeneration, here we investigated the effects of Rg1 on the BMSCs of a D-gal-induced aged rat model.
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Although the first multicenter studies focused on PM10 as the main exposure (Katsouyanni et al. 2001; Samet et al. 2000), more recently interest has shifted to specific PM fractions, constituents, and sources, with the aim of better elucidating the underlying biological mechanisms.
Integration with other genomic resources including PACdb (28), a database for cell-based pharmacogenomics, may help to better elucidate the mechanisms underlying genetic variants implicated in drug response traits, which have been widely investigated using this model.
Further studies are needed in order to better elucidate the neurobiological mechanisms underlying adipokines dysfunction in both episodic and chronic migraine.
On page 4, the authors state their motivation for the study as "To better elucidate the transcriptional mechanisms underlying Th cell identity…".
Moreover, to better elucidate the possible pathological mechanisms underlying inflammatory and immunological processes, they studied the amount of activated immune cells in the blood of FSHD patients and their expression of cytokines and other immune regulators.
5, 12 Although we found some factors that were related to better glycemic control, future clinical studies should elucidate the underlying pathophysiological mechanisms (eg, insulin sensitivity, beta-cell function).
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