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We found that both algorithms have good discrimination and calibration, but the WPS appeared to have better discriminatory power than the REMS system.
The value of a DOR ranges from 0 to infinity, with higher values indicating better discriminatory performance or higher accuracy of the test [43] [45].
However, we consistently observed better discriminatory performance of the assay when performed with samples taken from patients three weeks after exposure to the 2009 H1N1 influenza virus.
A stepwise logistic regression analysis including only protein markers resulted in a model with the three markers Ba, C3d and factor D. The corresponding ROC curve showed an even better discriminatory accuracy (AUC = 0.816; p = 0.05).
A higher lnDOR value indicates a better discriminatory test performance.
More detailed exposure assessments may result in better discriminatory abilities.
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The higher the value, the better the discriminatory test performance is [ 18].
As shown above, the new system had better homogeneity, discriminatory ability, and monotonicity of gradients.
The meta-gene list discriminating between ductal and lobular breast tumor samples at the mRNA level requires further confirmation at the protein level to better assess discriminatory power.
To interpret such data, mathematical modelling coupled to state-of-the-art statistical inference thus becomes a necessity (May 2004; Buchholz et al., 2013; Gerlach et al., 2013) to make sense of data and design better, more discriminatory experiments.
We also calculated diagnostic odds ratios the ratio of the odds of positivity in sCJD cases relative to the odds of positivity in the controls to assess which combinations of criteria patterns yielded better test discriminatory performance; 95% confidence intervals of the diagnostic odds ratios were estimated by the exact method.
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CEO of Professional Science Editing for Scientists @ prosciediting.com