Exact(1)
Tumor parenchyma is better differentiated with SWI compared with conventional MR images including contrast-enhanced T1.
Similar(59)
MRI is promising for T staging of GC as individual layers may be better differentiated compared with CT.
High grade tumours (Gleason grade 5 disease) expressed SPRY2 at lower levels than better differentiated tumours with Gleason grade ≤4 (Fig 1A).
Treated tumors are better differentiated as compared with those established in the control mice.
Other external validation based on populations with better differentiated stage I disease as well as histologic and surgical procedures are essential to complete this work.
Importantly, positive staining of ERα and AR was more frequently observed in patients with better differentiated tumors, intestinal type, and earlier TNM stage.
If anything, patients with more aggressive tumours (GIII/GIV) tended to present faster to a doctor than women with better differentiated tumours (GI/GII), and patient delay was somewhat shorter among women who noticed a lump as first symptom compared to other women.
Older age (over 70 years) was associated with smaller DCIS size and better differentiated tumours (P = 0.05) compared with women aged 50 69 years.
Moreover, in breast cancer, DR4, in contrast to DR5, has been shown to be more strongly expressed in better differentiated tumors, and correlated positively with surrogate markers of a better prognosis (hormone receptor status, Bcl-2, negative nodal status), but negatively with the expression of Her2/neu and the proliferation marker Ki67 [46].
In addition, the CD44 was linked with the better differentiated HNSCC.
Recently, fibrosarcoma cells overexpressing VEGF-A alone were found to generate better differentiated, narrower and pericyte-coated vessels with reduced hyperpermeability and greater resistance to vascular disrupting agents (Tozer et al, 2008).
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