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As well as aiding the design of vaccines and therapeutic drugs, scientists hope that the discovery will help develop better diagnostic tests for the virus, and throw light on the way the virus infects cells.
Diadexus' main focus is finding better diagnostic tests for deadly tumors of the prostate, colon, lung, breast, bladder and ovary.
Several attempts have been made towards the development of better diagnostic tests for TB [ 1].
However an urgent need exists for better diagnostic tests for VL in East Africa.
Given the poor concordance between diagnostic tests, our study suggests the urgent need for new and better diagnostic tests for LTBI, especially among HIV-infected persons who are at greatest risk for progression to active TB disease following infection.
Although novel tests for pediatric TB and EPTB are likely to reduce TB mortality, major reductions in pediatric and EPTB incidence and mortality also require better diagnostic tests for adult pulmonary TB that reach a larger population.
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The new results might also point to a better diagnostic test for ongoing inflammation in the arteries, says Samuel Wright, an atherosclerosis researcher at Merck Research Laboratories in Rahway, New Jersey.
In order to devise a better diagnostic test for ricin, the IPCR assay was adapted for the detection of ricin in biological samples collected from mice after intoxication.
This data also supports the conclusion from other studies that Hp-MMP 9 serum concentration is a better diagnostic test for lung damage than free Hp serum concentration [ 1].
Based on the findings of our study it appears that TSPOT may be a better diagnostic test for LTBI in HIV positive persons, as results do not depend on CD4 count.
Future applications of metabolic models will contribute to the understanding of microbial genomes and may lead to better diagnostic tests and therapies for human diseases [ 13].
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