Exact(5)
A more robust and better designed study was also released this month that found no association with coffee consumption and the risk of miscarriage.
This uncertainty can, in principle, be reduced by performing a larger or better designed study.
In theory, this was a better designed study than the 1992 one; however, inexplicably, all patients were allocated to the "bromocriptine first" group.
However, better designed study cohorts, which include serology as well as PCR detection of the virus are required in order to address the question whether the host genetic background has a major role in fatal EEHV disease.
The study was not placebo-controlled or blinded, so the authors followed it up with a better designed study that was published three years later (Sabe et al., 1995).
Similar(55)
Better designed studies are needed to clarify the many controversial questions in antifungal prophylaxis and therapy.
Better designed studies are needed, particularly for investigation of neurodegenerative diseases and effects on infants and children.
Better designed studies would reduce the risk of over-estimates of effect sizes and subsequent failure to replicate.
That, he says, was exactly what the early research tended to find--until better designed studies found that, while hit hard initially, many birds and other species bounced back fairly quickly ( Science, 9 April 1999, p. 247).
TR and TF access methods seem to be associated with similar early outcomes in patients undergoing non-coronary endovascular angioplasty and/or stenting although paucity of data necessitates the conduction of better designed studies.
Last, reliable assessment of the effectiveness of other surgical interventions such as intraspinous spacers and dynamic stabilization will require better designed studies that directly compare these techniques to other, more established, procedures.
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